CD2BP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49328

Novus Biologicals, part of Bio-Techne
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NBP2-49328
NBP2-49328-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CD2BP2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MPKRKVTFQGVGDEEDEDEIIVPKKKLVDPVAGSGGPGSRFKGKHSLDSDEE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CD2BP2 Antibody

Immunocytochemistry/ Immunofluorescence: CD2BP2 Antibody [NBP2-49328]

Immunocytochemistry/ Immunofluorescence: CD2BP2 Antibody [NBP2-49328]

Immunocytochemistry/Immunofluorescence: CD2BP2 Antibody [NBP2-49328] - Analysis of human cell line MCF7 shows positivity in nucleus & nucleoli.
Immunohistochemistry-Paraffin: CD2BP2 Antibody [NBP2-49328]

Immunohistochemistry-Paraffin: CD2BP2 Antibody [NBP2-49328]

Immunohistochemistry-Paraffin: CD2BP2 Antibody [NBP2-49328] - Staining in human fallopian tube and skeletal muscle tissues using anti-CD2BP2 antibody. Corresponding CD2BP2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: CD2BP2 Antibody [NBP2-49328]

Immunohistochemistry-Paraffin: CD2BP2 Antibody [NBP2-49328]

Immunohistochemistry-Paraffin: CD2BP2 Antibody [NBP2-49328] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.
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Applications for CD2BP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD2BP2

CD2BP2 is an intracellular protein which binds to a site containing two PPPGHR segments within the cytoplasmic region of CD2. Mutagenesis and NMR analysis demonstrated that the CD2 binding region of CD2BP2 includes a 17 amino acid motif also found in several yeast and Caenorhabditis elegans proteins of unknown function. In Jurkat T cells, over expression of the isolated CD2BP2 domain binding to CD2 enhances the production of interleukin 2 on crosslinking of CD2 but not the T cell receptor.

Alternate Names

CD2 (cytoplasmic tail) binding protein 2, CD2 antigen (cytoplasmic tail) binding protein 2, CD2 antigen (cytoplasmic tail)-binding protein 2, CD2 antigen cytoplasmic tail-binding protein 2, CD2 binding protein 2, CD2 cytoplasmic domain binding protein 2, CD2 cytoplasmic domain-binding protein 2, CD2 tail-binding protein 2, FWP010, KIAA1178, LIN1, Snu40, U5 snRNP 52K protein, U5-52K

Gene Symbol

CD2BP2

Additional CD2BP2 Products

Product Documents for CD2BP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD2BP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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