CD3 epsilon Antibody

Validated:

Cited:

Validated:

Cited:

Unconjugated

Polyclonal Rabbit IgG

0.2 mg/ml

A synthetic peptide aa156-168 (ERPPPVPNPDYEP) from human CD3 epsilon (Uniprot: P07766)

Predicted to react with Ape, Orangutan, Gibbon, Chimpanzee, Monkey, Elephant, Equine, Bovine, Sheep, Porcine, Canine, Feline, Rabbit, Rat, Mouse, Guinea Pig, Hamster, Opossum, Frog, Chicken.

Cell surface and cytoplasmic

Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

T-Cell Marker

Polyclonal

Rabbit

IgG

20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

200ug/ml of antibody purified from rabbit anti-serum by Protein A. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0 mg/ml. (NBP2-33116)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Protein A purified

10 mM PBS with 0.05% BSA

0.05% Sodium Azide

0.2 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C.