CD30/TNFRSF8 Antibody (CL12632)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18541

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL12632

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CD30/TNFRSF8 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a sythetic peptide for P28908. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for CD30/TNFRSF8 Antibody (CL12632)

Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (CL12632) [NBP3-18541]

Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (CL12632) [NBP3-18541]

Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (CL12632) [NBP3-18541] - Staining of human tonsil shows moderate membranous positivity in germinal center cells.
Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (CL12632) [NBP3-18541]

Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (CL12632) [NBP3-18541]

Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (CL12632) [NBP3-18541] - Staining of human testis cancer (embryonal carcinoma) shows moderate membranous positivity in tumor cells.
Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (CL12632) [NBP3-18541]

Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (CL12632) [NBP3-18541]

Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (CL12632) [NBP3-18541] - Staining of human ovarian cancer (dysgeminoma) shows moderate membranous positivity in tumor cells.
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Applications for CD30/TNFRSF8 Antibody (CL12632)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For use with IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD30/TNFRSF8

CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. (1,2) Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. (1) In anti-CD3epsilon-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN; production. (1) While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.

Alternate Names

CD30, TNFRSF8

Gene Symbol

TNFRSF8

Additional CD30/TNFRSF8 Products

Product Documents for CD30/TNFRSF8 Antibody (CL12632)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD30/TNFRSF8 Antibody (CL12632)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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