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CD35 Antibody (HB-8592) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09019

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-09019-0.025mg
NBP3-09019-0.2mg

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 kappa Clone # HB-8592

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Animals were immunized with purified CR1 from human erythrocytes. Spleen cells were fused with P3X63Ag8.653 myeloma cells.

Specificity

The antibody binds to a site distinct from the C3b binding site, and can be used to measure the number of receptors despite occupancy by ligand.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for CD35 Antibody (HB-8592) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody has been used for analysis of the expression of the CR1 receptor on human leukemia-derived CD4+ T cell lines by flow cytometry (Yaskanin 1995).

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD35

CD35 encodes a membrane glycoprotein found on peripheral blood cells, glomerular podocytes, and follicular dendritic cells. The protein is a receptor for complement components C3b and C4b and regulates the activity of the complement cascade. Variation in this protein is the basis of the Knops blood group system. The two most common alleles, F and S, differ by 8 exons and are thought to be the result of an unequal crossover event. A secreted form of the protein present in plasma has been described, but its full length nature has not been determined.

Alternate Names

C3BR, CD35, CR1, KN

Gene Symbol

CR1

Additional CD35 Products

Product Documents for CD35 Antibody (HB-8592) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD35 Antibody (HB-8592) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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