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CD43/Sialophorin Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33746

Novus Biologicals, part of Bio-Techne
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NBP2-33746
NBP2-33746-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: VTVTVGGSGGDKGSGFPDGEGSSRRPTLTTFFGRRKSRQGSLAMEELKSGSGPSLKGEEEPLVASEDGAVDAPAPDEPEG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CD43/Sialophorin Antibody - BSA Free

Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody [NBP2-33746]

Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody [NBP2-33746]

Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody [NBP2-33746] - Staining in human lymph node and cerebral cortex tissues using anti-SPN antibody. Corresponding SPN RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody [NBP2-33746]

Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody [NBP2-33746]

Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody [NBP2-33746] - Staining of human lymph node shows high expression.
Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody [NBP2-33746]

Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody [NBP2-33746]

Immunohistochemistry-Paraffin: CD43/Sialophorin Antibody [NBP2-33746] - Staining of human cerebral cortex shows low expression as expected.

Applications for CD43/Sialophorin Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD43

CD43 is a key glycoprotein of thymocytes and T lymphocytes, which affects the physicochemical properties of the T-cell surface and plays a role in lectin binding. This antibody contains an extended rodlike structure that may protrude above the glycocalyx of the cell, allowing accessibility of multiple glycan chains for binding. During T-cell activation CD43 is actively removed from the T-cell-antigen-presenting cell contact site, thus suggesting CD43's role in negative regulation of the adaptive immune response.

Long Name

Cluster of Differentiation 43

Alternate Names

CD43, GPL115, Leukosialin, LSN, Ly-48, Sialophorin, SPN

Gene Symbol

SPN

UniProt

Additional CD43 Products

Product Documents for CD43/Sialophorin Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD43/Sialophorin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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