CD44 Antibody (CD44V6/9400R)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23607

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-23607-100ug
NBP3-23607-20ug
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # CD44V6/9400R

Concentration

0.2 mg/ml

View all CD44 Antibodies »

Product Specifications

Immunogen

Recombinant fragment corresponding to the v3-v10 domain of human CD44

Localization

Cell surface.

Specificity

This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44.

Marker

Marker of Tumor Metastasis

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Description

Store at 2 to 8C. Non-hazardous. No MSDS required.

Scientific Data Images for CD44 Antibody (CD44V6/9400R)

CD44 Antibody (CD44V6/9400R) Immunohistochemistry-Paraffin: CD44 Antibody (CD44V6/9400R) [NBP3-23607] -

Immunohistochemistry-Paraffin: CD44 Antibody (CD44V6/9400R) [NBP3-23607] -

Immunohistochemistry-Paraffin: CD44 Antibody (CD44V6/9400R) [NBP3-23607] - Formalin-fixed, paraffin-embedded human esophagus stained with CD44 Antibody (CD44V6/9400R). Inset: PBS instead of primary antibody; secondary only negative control.

Applications for CD44 Antibody (CD44V6/9400R)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: CD44

CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.1-6

Alternate Names

CD44, ECMR-III, HCAM, HCELL, LHR, MDU2, MDU3, MIC4, MUTCH-I, Pgp1

Gene Symbol

CD44

Additional CD44 Products

Product Documents for CD44 Antibody (CD44V6/9400R)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD44 Antibody (CD44V6/9400R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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