CD46 Antibody (3F1) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52854

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3F1

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all CD46 Antibodies »

Product Summary for CD46 Antibody (3F1) - Azide and BSA Free

Immunogen

Recombinant CD46 protein

Specificity

Monoclonal antibody reacts specifically with 44 kDa protein. Diffuse and duplicated bands can be seen due to the glycosylation of CD46.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CD46 Antibody (3F1) - Azide and BSA Free

Immunohistochemistry-Paraffin: CD46 Antibody (3F1) - Azide and BSA Free [NBP1-52854]

Immunohistochemistry-Paraffin: CD46 Antibody (3F1) - Azide and BSA Free [NBP1-52854]

Immunohistochemistry-Paraffin: CD46 Antibody (3F1) [NBP1-52854] - Stained Placenta

Applications for CD46 Antibody (3F1) - Azide and BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Lyophilized powder, reconstituted in distilled water.

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD46

CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.

Alternate Names

CD46, MCP

Gene Symbol

CD46

Additional CD46 Products

Product Documents for CD46 Antibody (3F1) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD46 Antibody (3F1) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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