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CD79B Antibody (HM79-12) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28143

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation, Western Blot

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Armenian Hamster IgG1 Clone # HM79-12

Concentration

0.1 mg/ml

Product Summary for CD79B Antibody (HM79-12) [PE]

Immunogen

CD79alpha/CD79B heterodimers purified from mouse (BALB/c x NZB)F1 B cell lymphoma cells, WEHI231

Reactivity Notes

Mouse.

Specificity

beta chain of the mouse B-cell receptor, Mr 23 kDa

Clonality

Monoclonal

Host

Armenian Hamster

Isotype

IgG1

Scientific Data Images for CD79B Antibody (HM79-12) [PE]

Flow Cytometry: CD79B Antibody (HM79-12) [PE] [NBP1-28143] - Analysis of C57BL/6 splenocytes.

Applications for CD79B Antibody (HM79-12) [PE]

Application
Recommended Usage

Flow Cytometry

0.2 ug/10^6 cells

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS and a stabilizing agent

Preservative

Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CD79B

Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79alpha/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (1)

Alternate Names

B29, CD79B, IGB

Gene Symbol

CD79B

Additional CD79B Products

Product Documents for CD79B Antibody (HM79-12) [PE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD79B Antibody (HM79-12) [PE]

Protect conjugated forms from light.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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