Key Product Details

Species Reactivity

Validated:

Xenopus

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse Clone # BT2.1

Format

BSA Free

Concentration

1 mg/ml

View all Cdc20 Antibodies »

Product Summary for Cdc20 [p Thr79] Antibody (BT2.1) - BSA Free

Immunogen

GPKMQGpTPSRAG. pT represents phosphorylated Thr79.

Modification

p Thr79

Clonality

Monoclonal

Host

Mouse

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications for Cdc20 [p Thr79] Antibody (BT2.1) - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Western Blot

1:100 - 1:2000
Application Notes
Positive control(s): Xenopus egg extract.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cdc20

CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.

Long Name

Cell division cycle protein 20 homolog

Alternate Names

p55CDC

Gene Symbol

CDC20

Additional Cdc20 Products

Product Documents for Cdc20 [p Thr79] Antibody (BT2.1) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Cdc20 [p Thr79] Antibody (BT2.1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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