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CDC37 Antibody (3C7)

Novus Biologicals, part of Bio-Techne | Catalog # H00011140-M01

Novus Biologicals, part of Bio-Techne
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H00011140-M01

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3C7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

CDC37 (AAH08793.1, 1 a.a. ~ 378 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MMDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKIADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHVQRCIDSGLWVPNSKASEAKEGEEAGPGDPLLEAVPKTGDEKDVSV

Reactivity Notes

Other species not tested.

Localization

Cytoplasmic and Nuclear

Specificity

CDC37 - CDC37 cell division cycle 37 homolog (S. cerevisiae)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CDC37 Antibody (3C7)

Western Blot: CDC37 Antibody (3C7) [H00011140-M01]

Western Blot: CDC37 Antibody (3C7) [H00011140-M01]

Western Blot: CDC37 Antibody (3C7) [H00011140-M01] - CDC37 monoclonal antibody (M01), clone 3C7. Analysis of CDC37 expression in HL-60.
Immunocytochemistry/ Immunofluorescence: CDC37 Antibody (3C7) [H00011140-M01]

Immunocytochemistry/ Immunofluorescence: CDC37 Antibody (3C7) [H00011140-M01]

Immunocytochemistry/Immunofluorescence: CDC37 Antibody (3C7) [H00011140-M01] - Analysis of monoclonal antibody to CDC37 on HeLa cell. Antibody concentration 10 ug/ml.
Immunohistochemistry-Paraffin: CDC37 Antibody (3C7) [H00011140-M01]

Immunohistochemistry-Paraffin: CDC37 Antibody (3C7) [H00011140-M01]

Immunohistochemistry-Paraffin: CDC37 Antibody (3C7) [H00011140-M01] - Analysis of monoclonal antibody to CDC37 on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. Antibody concentration 1 ug/ml.

Applications for CDC37 Antibody (3C7)

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry

1:10-1:500

Western Blot

1:500
Application Notes
Antibody reactive against recominant protein and cell lysate for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin), and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CDC37

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Alternate Names

CDC37 (cell division cycle 37, S. cerevisiae, homolog), CDC37 cell division cycle 37 homolog, CDC37 cell division cycle 37 homolog (S. cerevisiae), CDC37A, cell division cycle 37 homolog (S. cerevisiae), Hsp90 chaperone protein kinase-targeting subunit, hsp90 co-chaperone Cdc37, p50Cdc37

Entrez Gene IDs

11140 (Human)

Gene Symbol

CDC37

OMIM

605065 (Human)

Additional CDC37 Products

Product Documents for CDC37 Antibody (3C7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CDC37 Antibody (3C7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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