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CDC37 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-70346

Novus Biologicals, part of Bio-Techne
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NBP1-70346

Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 324 to 374 of human cell division cycle 37 using the numbering given in entry NP_008996.1 (GeneID 11140).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CDC37 Antibody

Western Blot: CDC37 Antibody [NBP1-70346]

Western Blot: CDC37 Antibody [NBP1-70346]

Western Blot: CDC37 Antibody [NBP1-70346] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Affinity purified rabbit anti-CDC37 antibody used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. CDC37 was also immunoprecipitated by another rabbit anti-CDC37 antibody , which recognizes an upstream epitope.

Applications for CDC37 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CDC37

Cell division cycle 37 protein (CDC37) is also known as Hsp90 co-chaperone Cdc37. CDC37 is highly similar to Cdc37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form a complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [taken from NCBI Entrez Gene (GeneID: 11140)].

Alternate Names

CDC37 (cell division cycle 37, S. cerevisiae, homolog), CDC37 cell division cycle 37 homolog, CDC37 cell division cycle 37 homolog (S. cerevisiae), CDC37A, cell division cycle 37 homolog (S. cerevisiae), Hsp90 chaperone protein kinase-targeting subunit, hsp90 co-chaperone Cdc37, p50Cdc37

Gene Symbol

CDC37

Additional CDC37 Products

Product Documents for CDC37 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CDC37 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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