Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CDIP Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the center of human CDIP. The immunogen is located within amino acids 40 - 90 of CDIP. Amino Acid Squence: GPPPYEPPGHPMPQPG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CDIP Antibody - BSA Free

Western Blot: CDIP AntibodyBSA Free [NBP1-76993]

Western Blot: CDIP AntibodyBSA Free [NBP1-76993]

Western Blot: CDIP Antibody [NBP1-76993] - Human brain lysate with CDIP antibody at (A) 1 and (B) 2 ug/ml.
CDIP Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: CDIP Antibody - BSA Free [NBP1-76993] -

Immunocytochemistry/ Immunofluorescence: CDIP Antibody - BSA Free [NBP1-76993] - Immunofluorescence of CDIP1 in mouse brain tissue with CDIP1 antibody at 20 ug/mL.
CDIP Antibody - BSA Free

Immunohistochemistry: CDIP Antibody - BSA Free [NBP1-76993] -

Immunohistochemistry: CDIP Antibody - BSA Free [NBP1-76993] - Immunohistochemistry of FNIP2 in mouse brain tissue with FNIP2 antibody at 2.5 ug/mL.

Applications for CDIP Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CDIP

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.

Alternate Names

CDIP, cell death inducing protein, Cell death-inducing protein, chromosome 16 open reading frame 5, I1, LITAF-like protein, Transmembrane protein I1

Entrez Gene IDs

29965 (Human); 66626 (Mouse)

Gene Symbol

CDIP1

UniProt

Q9H305 (Human)

Additional CDIP Products

Product Documents for CDIP Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CDIP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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