CDX2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77113

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (90%), Chicken (94%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CDX2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CDX2. The immunogen is located within amino acids 220 - 270 of CDX2. Amino Acid Squence: FQNRRAKERKINKKKL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

34 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CDX2 Antibody - BSA Free

Western Blot: CDX2 AntibodyBSA Free [NBP1-77113]

Western Blot: CDX2 AntibodyBSA Free [NBP1-77113]

Western Blot: CDX2 Antibody [NBP1-77113] - Mouse brain tissue lysate at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: CDX2 Antibody - BSA Free [NBP1-77113]

Immunocytochemistry/ Immunofluorescence: CDX2 Antibody - BSA Free [NBP1-77113]

Immunocytochemistry/Immunofluorescence: CDX2 Antibody [NBP1-77113] - Immunofluorescence of CDX2 in rat brain tissue with CDX2 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: CDX2 Antibody - BSA Free [NBP1-77113]

Immunohistochemistry-Paraffin: CDX2 Antibody - BSA Free [NBP1-77113]

Immunohistochemistry-Paraffin: CDX2 Antibody [NBP1-77113] - Rat brain tissue with CDX2 antibody at 5 ug/mL.

Applications for CDX2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CDX2

CDX2 is a member of the caudal homeobox family of transcription factors that also includes the proteins CDX1 and CDX4. CDX2 is strongly expressed in the trophectoderm in the blastocyst with expression maintained within the proliferating extra-embryonic ectoderm during development. It is required for the repression of the transcription of the POU5F1/Oct4 and NANOG genes in the outer cells of the blastocyst and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Aberrant expression of CDX2 is associated with numerous types of carcinomas, including intestinal metaplasia, gastric carcinoma, and acute myeloid leukemia due to deregulated HOX gene expression.

Long Name

Caudal-type Homeobox Transcription Factor 2

Alternate Names

CDX3

Entrez Gene IDs

1045 (Human); 12591 (Mouse); 66019 (Rat)

Gene Symbol

CDX2

UniProt

Q99626

Additional CDX2 Products

Product Documents for CDX2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CDX2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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