CDYL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB300-874

Novus Biologicals, part of Bio-Techne
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NB300-874
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all CDYL Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SMLKYLQRKIDEF corresponding to C-Terminus according to NP_004815.3, NP_001137442.1, NP_001137443.1.

Specificity

This antibody is expected to recognize both eported isoforms NP_004815.3; NP_001137442.1; NP_001137443.1). Variants (NP_001137442.1; NP_001137443.1) encode the same isoform.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CDYL Antibody

Western Blot: CDYL Antibody [NB300-874]

Western Blot: CDYL Antibody [NB300-874]

Western Blot: CDYL Antibody [NB300-874] - (1ug/ml) of Human Testes lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Applications for CDYL Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:4000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 75 kDa band observed in human testis lysates is reported in scientific literature (PMID: 12072557). An additional band of unknown identity was also consistently observed at 26 kDa. This band was successfully blocked by incubation with the immunizing peptide.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CDYL

Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.

Alternate Names

CDYL1bA620A17.2 (chromodomain protein, Y chromosome-like), CDY-like, CDY-like, autosomal, chromodomain protein, Y chromosome-like, chromodomain protein, Y-like, chromodomain Y-like protein, DKFZp586C1622, EC 2.3.1.48, MGC131936, testis-specific chromodomain Y-like protein

Entrez Gene IDs

9425 (Human); 12593 (Mouse)

Gene Symbol

CDYL

UniProt

NP_004815 (Human)

Additional CDYL Products

Product Documents for CDYL Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CDYL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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