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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI3D8

Concentration

1 mg/ml

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 35-680 of human CEACAM5 (NP_004354) produced in SF9 cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for CEACAM5/CD66e Antibody (OTI3D8)

Western Blot: CEACAM5/CD66e Antibody (OTI3D8) [NBP2-46231]

Western Blot: CEACAM5/CD66e Antibody (OTI3D8) [NBP2-46231]

Western Blot: CEACAM-5/CD66e Antibody (3D8) [NBP2-46231] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CEACAM-5.
Immunohistochemistry: CEACAM5/CD66e Antibody (OTI3D8) [NBP2-46231]

Immunohistochemistry: CEACAM5/CD66e Antibody (OTI3D8) [NBP2-46231]

Immunohistochemistry: CEACAM-5/CD66e Antibody (3D8) [NBP2-46231] - Analysis of Human tonsil tissue.
Immunohistochemistry: CEACAM5/CD66e Antibody (OTI3D8) [NBP2-46231]

Immunohistochemistry: CEACAM5/CD66e Antibody (OTI3D8) [NBP2-46231]

Immunohistochemistry: CEACAM-5/CD66e Antibody (3D8) [NBP2-46231] - Analysis of Human colon tissue.

Applications for CEACAM5/CD66e Antibody (OTI3D8)

Application
Recommended Usage

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CEACAM-5/CD66e

The CD66e (CEA; 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion. Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting.

Long Name

Carcinoembryonic Antigen-related Cell Adhesion Molecule 5

Alternate Names

CD66e, CEA, CEACAM5

Gene Symbol

CEACAM5

Additional CEACAM-5/CD66e Products

Product Documents for CEACAM5/CD66e Antibody (OTI3D8)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CEACAM5/CD66e Antibody (OTI3D8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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