CEBP alpha Antibody (C5) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41782

Novus Biologicals, part of Bio-Techne
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NBP3-41782
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Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # C5

Format

BSA Free

Concentration

1 mg/ml

View all CEBP alpha Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Rat CEBP alpha (Uniprot#: P05554; Ala72-Ala358 (Uniprot#: P05554)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CEBP alpha Antibody (C5) - BSA Free

CEBP alpha Antibody (C5)

Western Blot: CEBP alpha Antibody (C5) [NBP3-41782] -

Western Blot: CEBP alpha Antibody (C5) [NBP3-41782] - Sample: Lane1: U937 cell lysate; Lane2: THP1 cell lysate Primary Ab: 0.2ug/ml NBP3-41782; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

Applications for CEBP alpha Antibody (C5) - BSA Free

Application
Recommended Usage

Western Blot

0.2-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Format

BSA Free

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CEBP alpha

CCAAT/enhancer-binding proteins (C/EBP) consist of a family of transcription factors that play an important role in regulating the balance between cell growth & differentiation. The various isoforms of C/EBP (alpha, beta, gamma, delta, epsilon, zeta) exhibit similar DNA-binding specificities and contain a leucine zipper dimerization domain (1). C/EBP alpha (2) can form heterodimers with related protein C/EBP beta and gamma. C/EBP alpha directly interacts with CDK2and CDK4 and arrests cell proliferation by inhibiting these kinases (3). C/EBP alpha has been shown to bind to the promoter and modulate the expression of leptin, a protein that plays an important role in body weight homeostasis (4). C/EBP alpha also has prominent antimitotic activity and may play a role of a tumor suppressor.

Long Name

CCAAT/enhancer-Binding Protein alpha

Alternate Names

C/EBP-alpha, CEBPA

Gene Symbol

CEBPA

Additional CEBP alpha Products

Product Documents for CEBP alpha Antibody (C5) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CEBP alpha Antibody (C5) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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