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Centaurin alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31179

Novus Biologicals, part of Bio-Techne
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NBP1-31179

Key Product Details

Species Reactivity

Validated:

Human, Rat

Predicted:

Bovine (100%), Mouse (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Centaurin alpha 1. The exact sequence is proprietary.

Localization

Nucleus, Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Centaurin alpha 1 Antibody

Western Blot: Centaurin alpha 1 Antibody [NBP1-31179]

Western Blot: Centaurin alpha 1 Antibody [NBP1-31179]

Western Blot: Centaurin alpha 1 Antibody [NBP1-31179] - Sample(30 ug of whole cell lysate)A: A431 B: HeLaS3 7. 5% SDS PAGE, antibody diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: Centaurin alpha 1 Antibody [NBP1-31179]

Immunocytochemistry/ Immunofluorescence: Centaurin alpha 1 Antibody [NBP1-31179]

Immunocytochemistry/Immunofluorescence: Centaurin alpha 1 Antibody [NBP1-31179] - Centaurin alpha 1 antibody [C3], C-term detects Centaurin alpha 1 protein by immunofluorescent analysis.Sample: DIV9 rat E18 primary hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: Centaurin alpha 1 stained by Centaurin alpha 1 antibody [C3], C-term (NBP1-31179).Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody.Blue: Fluoroshield with DAPI.
Immunohistochemistry-Paraffin: Centaurin alpha 1 Antibody [NBP1-31179]

Immunohistochemistry-Paraffin: Centaurin alpha 1 Antibody [NBP1-31179]

Immunohistochemistry-Paraffin: Centaurin alpha 1 Antibody [NBP1-31179] - Paraffin-embedded gastric tissue, using antibody at 1:100 dilution.

Applications for Centaurin alpha 1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Centaurin alpha 1

The centaurin alpha 1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2 adrenoceptor internalization and negatively regulates ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP.

Alternate Names

arf-GAP with dual PH domain-containing protein 1, ArfGAP with dual PH domains 1, CENTA1centaurin-alpha-1, centaurin, alpha 1, centaurin-alpha, Centaurin-alpha-1, Cnt-a1, GCS1L, p42IP4, Putative MAPK-activating protein PM25

Gene Symbol

ADAP1

Additional Centaurin alpha 1 Products

Product Documents for Centaurin alpha 1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Centaurin alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.