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Ceramide Kinase Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-40450

Novus Biologicals, part of Bio-Techne
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NB110-40450

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Monkey (90%), Primate (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from N-terminal extracellular domain of human Ceramide Kinase.

Epitope

N-terminal extracellular domain of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (90%), Gibbon (90%), Marmoset (90%), Canine (85%), Bovine (80%), Rabbit (80%).

Specificity

Human CERK. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Ceramide Kinase Antibody - BSA Free

Immunohistochemistry-Paraffin: Ceramide Kinase Antibody - BSA Free [NB110-40450]

Immunohistochemistry-Paraffin: Ceramide Kinase Antibody - BSA Free [NB110-40450]

Immunohistochemistry-Paraffin: Ceramide Kinase Antibody - BSA Free [NB110-40450] - Analysis of anti-CERK antibody with human brain, cortex.

Applications for Ceramide Kinase Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

20 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Ceramide Kinase

CERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.

Long Name

Ceramide kinase

Alternate Names

CERK, EC 2.7.1.138, hCERK, KIAA1646, Lipid kinase 4, LK4

Entrez Gene IDs

64781 (Human)

Gene Symbol

CERK

Additional Ceramide Kinase Products

Product Documents for Ceramide Kinase Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Ceramide Kinase Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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