CETP Antibody (2F1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15191

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15191
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2F1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CETP Antibodies »

Product Summary for CETP Antibody (2F1)

Immunogen

A synthesized peptide derived from human CETP. UniProt ID (P11597).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CETP Antibody (2F1)

Immunohistochemistry: CETP Antibody (2F1) [NBP3-15191]

Immunohistochemistry: CETP Antibody (2F1) [NBP3-15191]

Immunohistochemistry: CETP Antibody (2F1) [NBP3-15191] - IHC image of CETP antibody diluted at 1:115 and staining in paraffin-embedded human liver tissue. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 minutes at RT. Then primary antibody (1% BSA) was incubated at 4C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Applications for CETP Antibody (2F1)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, and 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: CETP

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Long Name

Cholesteryl Ester Transfer Protein

Alternate Names

BPIFF, HDLCQ10, Lipid Transfer Protein I

Gene Symbol

CETP

Additional CETP Products

Product Documents for CETP Antibody (2F1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CETP Antibody (2F1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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