CETP Antibody (ATM192) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB300-558

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Bovine, Rabbit

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # ATM192

Format

BSA Free

Concentration

2 mg/ml

View all CETP Antibodies »

Product Summary for CETP Antibody (ATM192) - BSA Free

Immunogen

Synthetic peptide corresponding to residues C D(149) S G R V R T D A P D(159) of human CETP protein.

Localization

Secreted

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for CETP Antibody (ATM192) - BSA Free

Western Blot: CETP Antibody (ATM192)BSA Free [NB300-558]

Western Blot: CETP Antibody (ATM192)BSA Free [NB300-558]

Western Blot: CETP Antibody (ATM192) [NB300-558] - Analysis of human liver extract.
Immunocytochemistry/ Immunofluorescence: CETP Antibody (ATM192) - BSA Free [NB300-558]

Immunocytochemistry/ Immunofluorescence: CETP Antibody (ATM192) - BSA Free [NB300-558]

Immunocytochemistry/Immunofluorescence: CETP Antibody (ATM192) [NB300-558] - Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a CETP monoclonal antibody at a dilution of 1:20 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody and nuclei with DAPI (blue) is shown.

Applications for CETP Antibody (ATM192) - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Immunocytochemistry/ Immunofluorescence

1:20

Immunoprecipitation

1:10 - 1:500

Western Blot

1:400
Application Notes
WB: Detects adoublet at ~70 kDa from human serum representing CETP. May be useful in IP CETP activity from serum samples using protein G.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CETP

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Long Name

Cholesteryl Ester Transfer Protein

Alternate Names

BPIFF, HDLCQ10, Lipid Transfer Protein I

Entrez Gene IDs

1071 (Human)

Gene Symbol

CETP

UniProt

P11597

Additional CETP Products

Product Documents for CETP Antibody (ATM192) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CETP Antibody (ATM192) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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