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ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor® 350]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11984AF350

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-11984AF350

Key Product Details

Species Reactivity

Validated:

Mouse

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Alexa Fluor 350 (Excitation = 346 nm, Emission = 442 nm)

Antibody Source

Monoclonal Rabbit IgG Kappa Clone # BZ194

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor® 350]

Immunogen

This antibody was raised by immunising Wistar Furth rats with the mChemR23/CMKLR1 peptide/KLH conjugate. The immunizing amino-terminal mChemR23/CMKLR1 peptide with the sequence NH2-DSGIYDDEYSDGFGYFVDLEEASPWC-COOH, corresponding to residues residues 8-32 of mChemR23/CMKLR1, with a nonnative carboxyl-terminal cysteine to facilitate conjugation to keyhole limpet hemocyanin (KLH).

Specificity

This antibody is specific for murine serpentine receptor mChemR23/CMKLR1 (aka ChemR23, DEZ). mChemR23/CMKLR1 is a novel protein possessing high homology with members of the chemoattractant receptor family, and binds the chemoattractant chemerin. Selective mChemR23/CMKLR1 expression has been demonstrated by mouse macrophages ex vivo, and by dendritic cell precursors cultured in vitro.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Scientific Data Images for ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor® 350]

ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor® 350]

ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor® 350] [NBP3-11984AF350] -

ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor® 350] [NBP3-11984AF350] - Vial of Alexa Fluor 350 conjugated antibody. Alexa Fluor 350 is optimally excited at 346 nm by the UV laser (350 or 355 nm) and has an emission maximum of 442 nm.

Applications for ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor® 350]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ChemR23

Chemokine-Like Receptor 1 (CMKLR1) is an chemoattractant receptor. CMKLR1 is thought to act primarily in bone development where it is differentially regulated in osseous and cartilaginous tissue. It also acts as a coreceptor for immunodeficiency viruses. CMKLR1 has two variants that are produced by alternative splicing. Chemokine-like receptor 1 (CMKLR1) has been reported to be expressed in bone marrow, liver, appendix, thymus, lymph node, placenta, and spleen. ESTs have been isolated from human normal kidney and testis libraries and from a prostate cancer library.

Long Name

Chemokine-like Receptor 1/Orphan G Protein-coupled Receptor ChemR23

Alternate Names

cmklr1, Dez, Gpcr27

Gene Symbol

CMKLR1

Additional ChemR23 Products

Product Documents for ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor® 350]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ChemR23/CMKLR1 Antibody (BZ194) [Alexa Fluor® 350]



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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