Chimaerin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12460

Novus Biologicals, part of Bio-Techne
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NBP3-12460
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Chimaerin 2 Antibodies »

Product Specifications

Immunogen

Synthetic peptide taken within amino acid region 1-100 on human beta-chimaerin isoform 3 protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Chimaerin 2 Antibody

Western Blot: Chimaerin 2 Antibody [NBP3-12460]

Western Blot: Chimaerin 2 Antibody [NBP3-12460]

Western Blot: Chimaerin 2 Antibody [NBP3-12460] - WB 1:500 dilution

Applications for Chimaerin 2 Antibody

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: Chimaerin 2

Chimaerin 2 is a protein expressed in the brain and pancreas with two isoforms, measuring 468 and 332 amino acids in length with weights of approximately 54 and 38 kDa respectively. Chimaerin 2 functions as a GTP-ase activating protein for p21-rac, and a deficiency in this protein could lead to tumor progression. Current studies are being done on several diseases and disorders related to this protein including b-cell lymphomas, schizophrenia, sleeping sickness, insulin resistance, diabetic retinopathy, malignant glioma, nephropathy, spasticity, astrocytoma, and breast cancer. Chimaerin 2 has also been shown to have interactions with BAG6, NCK1, RAC1, ERBB3, and EIF3C in pathways such as the Rho GTPase cycle, signal transduction, and regulations of RAC1 activity pathways.

Alternate Names

ARHGAP3beta chimerin, BCH, beta-chimaerin, Beta-chimerin, chimerin (chimaerin) 2, MGC138360, Rho GTPase-activating protein 3, RhoGAP3, rho-GTPase-activating protein 3

Gene Symbol

CHN2

Additional Chimaerin 2 Products

Product Documents for Chimaerin 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Chimaerin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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