Our customer would like to have CHI3L1 antibody for testing samples from dog... After searching, none can be found. However, we noticed that the sequence of NBP1-57913 is listed clearly as well as similarities of other species. We wonder if you can help compare with canine CHI3L1 as well.

Name: Chitinase 3-like 1/YKL-40 Antibody
Brand: Novus Biologicals
SKU: NBP1-57913

We have five antibodies to CHI3L1, all of which are raised against the human protein. The sequence entry of canine CHI3L1 has not been reviewed in Uniprot, however I ran an alignment for you between this and the human sequence, and found the homology to be 82%. Therefore it is likely, but not confirmed, that antibodies which bind the human protein may recognise canine CHI3L1. The homology between the immunogen sequence used to generate NBP1-57913 and the full length canine sequence is 84%. The homology between the immunogen sequence used to generate NBP1-28610 and the full length canine sequence is 83%. Your customer may be interested in our Innovators Reward Program, which allows them to try our primary antibodies in an untested species or application without the financial risk of failure. They could try one of our CHI3L1 antibodies against canine samples, share their results (including an image) with us, and receive a voucher for 100% of the purchase price of the reviewed product.

Chitinase 3-like 1/YKL-40 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-57913

Submit a review

Product Datasheet / COA / SDS

100% Guarantee

Product Summary
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Monkey, Virus

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Chitinase 3-like 1/YKL-40 Antibodies »

Product Summary for Chitinase 3-like 1/YKL-40 Antibody

Immunogen

Synthetic peptides corresponding to CHI3L1(chitinase 3-like 1 (cartilage glycoprotein-39)) The peptide sequence was selected from the middle region of CHI3L1. Peptide sequence LDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRL. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Chitinase 3-like 1/YKL-40 Antibody

Western Blot: Chitinase 3-like 1/YKL-40 Antibody [NBP1-57913]

Western Blot: Chitinase 3-like 1 Antibody [NBP1-57913] - HepG2 tissue lysate at a concentration of 0.5ug/ml.

Immunocytochemistry/ Immunofluorescence: Chitinase 3-like 1/YKL-40 Antibody [NBP1-57913]

Immunocytochemistry/Immunofluorescence: Chitinase 3-like 1 Antibody [NBP1-57913] - simian immunodeficiency virus encephalitis Primary 1:2000 Secondary 1:200

Applications for Chitinase 3-like 1/YKL-40 Antibody

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:2000

Western Blot

1.0 ug/ml

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Chitinase 3-like 1/YKL-40

CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment. CHI3L1 may play a role in tissue remodeling and defense against pathogens. It belongs to the glycosyl hydrolase 18 family. CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment.

Alternate Names

CHI3L1, Chitinase 3 like 1, HCgp39, YKL-40

Gene Symbol

CHI3L1

UniProt

P36222

Additional Chitinase 3-like 1/YKL-40 Products

Product Documents for Chitinase 3-like 1/YKL-40 Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Chitinase 3-like 1/YKL-40 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Protocols
FAQs

Chitinase 3-like 1/YKL-40 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-57913

Key Product Details

Species Reactivity

Validated:

Applications

Validated:

Cited:

Label

Antibody Source

Concentration

View all Chitinase 3-like 1/YKL-40 Antibodies »

Product Summary for Chitinase 3-like 1/YKL-40 Antibody

Immunogen

Clonality

Host

Isotype

Description

Scientific Data Images for Chitinase 3-like 1/YKL-40 Antibody

Western Blot: Chitinase 3-like 1/YKL-40 Antibody [NBP1-57913]

Immunocytochemistry/ Immunofluorescence: Chitinase 3-like 1/YKL-40 Antibody [NBP1-57913]

Applications for Chitinase 3-like 1/YKL-40 Antibody

Immunocytochemistry/ Immunofluorescence

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: Chitinase 3-like 1/YKL-40

Alternate Names

Gene Symbol

UniProt

Additional Chitinase 3-like 1/YKL-40 Products

Product Documents for Chitinase 3-like 1/YKL-40 Antibody

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Chitinase 3-like 1/YKL-40 Antibody