Key Product Details

Species Reactivity

Human

Applications

ELISA, Radioimmunoassay, Radioimmunodiffusion

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # INN-hCG-24

Concentration

1.0 mg/ml

View all Chorionic Gonadotropin beta Chain (HCG beta) Antibodies »

Product Specifications

Immunogen

Purified human chorionic gonadotropin

Localization

Secreted

Specificity

This is a high affinity antibody recognising the beta 4 epitope on hCG. It is also reactive with hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, CTP-hCG, CTP-hCGbeta. It may be used in combination with INN hCG2, 32 and 45. It has minor cross reactivity with hLH and hLHbeta. No cross reaction is observed with hFSH, hTSH, or the glycoprotein hormone alpha chains.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications

Application
Recommended Usage

ELISA

1:100-1:2000
Application Notes
ELISA: Use at an assay dependent dilution. RIA: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Chorionic Gonadotropin beta Chain (HCG beta)

Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.

Long Name

Chorionic Gonadotropin beta Chain

Alternate Names

CG-Beta, CGB, CGB3, CGB5, CGB8, Choriogonadotropin Subunit Beta

Entrez Gene IDs

1082 (Human)

Gene Symbol

CGB3

UniProt

P01233 (Human)

Additional Chorionic Gonadotropin beta Chain (HCG beta) Products

Product Documents

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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