Key Product Details

Species Reactivity

Human

Applications

ELISA, Radioimmunodiffusion

Label

Janelia Fluor 585

Antibody Source

Monoclonal Mouse IgG1 Clone # INN-hCG-24

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Chorionic Gonadotropin beta Chain (HCG beta) Antibodies »

Product Specifications

Immunogen

Purified human chorionic gonadotropin

Reactivity Notes

Reacts with Human.

Localization

Secreted

Specificity

This is a high affinity antibody recognising the beta 4 epitope on hCG. It is also reactive with hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, CTP-hCG, CTP-hCGbeta. It may be used in combination with INN hCG2, 32 and 45. It has minor cross reactivity with hLH and hLHbeta. No cross reaction is observed with hFSH, hTSH, or the glycoprotein hormone alpha chains.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Radioimmunodiffusion

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Chorionic Gonadotropin beta Chain (HCG beta)

Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.

Long Name

Chorionic Gonadotropin beta Chain

Alternate Names

CG-Beta, CGB, CGB3, CGB5, CGB8, Choriogonadotropin Subunit Beta

Gene Symbol

CGB3

Additional Chorionic Gonadotropin beta Chain (HCG beta) Products

Product Documents

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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