Chromogranin A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-62464

Novus Biologicals, part of Bio-Techne
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NB100-62464
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Sheep IgG

Concentration

5 mg/ml

View all Chromogranin A Antibodies »

Product Summary for Chromogranin A Antibody

Immunogen

Synthetic peptide corresponding to the amino acids 1 - 15 (lpvnspmnkgdtevm) of the native molecule conjugated to Keyhole limpet Haemocyanin

Epitope

L-P-V-N-S-P-M-N-K-G-D-T-E-V-M

Reactivity Notes

Based on sequence similarity, is expected to react with:Bovine, Chimpanzee, Dog, Horse, Pig, Mouse, Rat

Localization

Neuroendocrine and endocrine secretory granules.

Specificity

This product recognizes human chromogranin A, a secreted peptide that inhibits glucose-induced insulin release.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Scientific Data Images for Chromogranin A Antibody

Immunohistochemistry-Paraffin: Chromogranin A Antibody - BSA Free [NB100-62464]

Immunohistochemistry-Paraffin: Chromogranin A Antibody - BSA Free [NB100-62464]

Immunohistochemistry-Paraffin: Chromogranin A Antibody [NB100-62464] - Paraffin embedded human pancreas with Sheep anti Human Chromogranin following pronase antigen retrieval.

Applications for Chromogranin A Antibody

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:25-1:100
Application Notes
For IHC, Pronase protein digestion pre-treatment of paraffin sections is required.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Chromogranin A

Chromogranin A (a protein of 439 amino acids which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

Alternate Names

Betagranin, Catestatin, CHGA, Chromofungin, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I

Entrez Gene IDs

1113 (Human)

Gene Symbol

CHGA

UniProt

P10645

Additional Chromogranin A Products

Product Documents for Chromogranin A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Chromogranin A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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