Claudin-11 Antibody (SR1352)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21885

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21885-100ul
NBP3-21885-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1352

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Claudin-11 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Claudin-11 (Uniprot #: O75508)

Specificity

Detects endogenous levels of total Claudin-11

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Claudin-11 Antibody (SR1352)

Western Blot: Claudin-11 Antibody (SR1352) [NBP3-21885] -

Western Blot: Claudin-11 Antibody (SR1352) [NBP3-21885] - Western blot analysis using NBP3-21885 in SH-SY5Y cell lysate.

Applications for Claudin-11 Antibody (SR1352)

Application
Recommended Usage

Flow Cytometry

1:100

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Claudin-11

Oligodendrocyte specific protein belongs is a major component of central nervous system myelin that is necessary for normal CNS function. The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, and are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that the Claudin 11 protein determines the permeability between layers of myelin sheaths via focal adhesion and with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

Alternate Names

Claudin11, CLDN11, OSP, OTM

Gene Symbol

CLDN11

Additional Claudin-11 Products

Product Documents for Claudin-11 Antibody (SR1352)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Claudin-11 Antibody (SR1352)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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