Claudin-6 Antibody (9H8)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26651

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # 9H8

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Claudin-6 Antibodies »

Product Specifications

Immunogen

Recombinant Human Claudin-6 protein [UniProt P56747]

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Scientific Data Images for Claudin-6 Antibody (9H8)

Claudin-6 Antibody (9H8)

ELISA: Claudin-6 Antibody (9H8) [NBP3-26651] -

ELISA: Claudin-6 Antibody (9H8) [NBP3-26651] - The Binding Activity of Human Claudin-6 with Claudin-6 Antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human Claudin-6 at 10 ug/mL can bind Claudin-6 Antibody, the EC50 is 1.501-2.035 ng/mL.
Claudin-6 Antibody (9H8)

Flow Cytometry: Claudin-6 Antibody (9H8) [NBP3-26651] -

Flow Cytometry: Claudin-6 Antibody (9H8) [NBP3-26651] - Untransfected HEK293T cells (green line) and transfected Human CLDN6 HEK293T stable cells (red line) were stained with anti-CLDN6/9 recombinant antibody (2ug/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

Applications for Claudin-6 Antibody (9H8)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50% Glycerol, 0.01M PBS, PH 7.4

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Claudin-6

The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule. Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-6 is expressed in differentiated F9 cells that resemble tight junction-bearing viceral endoderm resulting from stimulation with retinoc acid and mediated by RXRalpha and RARgamma. Claudin-6 is absent in mouse brain and lung. The human claudin-6 gene maps to chromosome 16p13.3.

Alternate Names

Claudin6, CLDN6, Skullin 2

Gene Symbol

CLDN6

Additional Claudin-6 Products

Product Documents for Claudin-6 Antibody (9H8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Claudin-6 Antibody (9H8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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