Claudin-7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85683

Novus Biologicals, part of Bio-Techne
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NBP1-85683
NBP1-85683-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Claudin-7 Antibodies »

Product Summary for Claudin-7 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKMYDSVLALS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Claudin-7 Antibody

Immunohistochemistry-Paraffin: Claudin-7 Antibody [NBP1-85683]

Immunohistochemistry-Paraffin: Claudin-7 Antibody [NBP1-85683]

Immunohistochemistry-Paraffin: Claudin-7 Antibody [NBP1-85683] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: Claudin-7 Antibody [NBP1-85683]

Immunohistochemistry-Paraffin: Claudin-7 Antibody [NBP1-85683]

Immunohistochemistry-Paraffin: Claudin-7 Antibody [NBP1-85683] - Staining of human rectum shows high expression.
Immunohistochemistry-Paraffin: Claudin-7 Antibody [NBP1-85683]

Immunohistochemistry-Paraffin: Claudin-7 Antibody [NBP1-85683]

Immunohistochemistry-Paraffin: Claudin-7 Antibody [NBP1-85683] - Staining in human rectum and skeletal muscle tissues using anti-CLDN7 antibody. Corresponding CLDN7 RNA-seq data are presented for the same tissues.

Applications for Claudin-7 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Claudin-7

The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. mRNA studies indicate that claudin-7 is specifically expressed in mouse lung and kidney, but not in heart, brain, spleen, liver, skeletal muscle or testis. The gene encoding human claudin-7 maps to chromosome 17p13.

Alternate Names

CEPTRL2, Claudin7, CLDN7, CPETRL2

Gene Symbol

CLDN7

Additional Claudin-7 Products

Product Documents for Claudin-7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Claudin-7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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