CLCA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1791

Novus Biologicals, part of Bio-Techne
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NB100-1791
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Peptide ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all CLCA1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-TVTSKTNKDTSK corresponding to internal region according to NP_001276.1.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 18314541).

Specificity

No cross-reactivity expected with CLCA2 and 3.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CLCA1 Antibody

Western Blot: CLCA1 Antibody [NB100-1791]

Western Blot: CLCA1 Antibody [NB100-1791]

Western Blot: CLCA1 Antibody [NB100-1791] (1ug/ml) staining of Human Duodenum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for CLCA1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Experiments gave bands at approx. 80 kDa band and 30 kDa band in human duodenum lysates. These bands correspond to earlier findings in scientific literature with different antibodies (Gruber et al, Genomics. 1998 Dec 1;54(2): 200-14.). This protein has a calculated MW of 100 kDa band according to NP_001276.1.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CLCA1

This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.

Long Name

Chloride Channel Accessory 1

Alternate Names

CaCC-1, CLCRG1, GOB5, HCLCA1

Entrez Gene IDs

1179 (Human)

Gene Symbol

CLCA1

UniProt

NP_001276.1 (Human)

Additional CLCA1 Products

Product Documents for CLCA1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CLCA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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