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CLCNKB Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10349

Novus Biologicals, part of Bio-Techne
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NBP3-10349-100ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Summary for CLCNKB Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CLCNKB (NP_000076). Peptide sequence ILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTSRGRAVGCVSW

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

76 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CLCNKB Antibody

Western Blot: CLCNKB Antibody [NBP3-10349]

Western Blot: CLCNKB Antibody [NBP3-10349]

Western Blot: CLCNKB Antibody [NBP3-10349] - Western blot analysis using NBP3-10349 on Human kidney as a positive control. Antibody Titration: 0.2-1 ug/ml

Applications for CLCNKB Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CLCNKB

Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.

Alternate Names

chloride channel KbClC-Kb, chloride channel protein ClC-Kb, chloride channel, kidney, B, ClC-K2, CLCKB, hClC-Kb, MGC24087

Gene Symbol

CLCNKB

Additional CLCNKB Products

Product Documents for CLCNKB Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CLCNKB Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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