CNPase Antibody - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-93362

Novus Biologicals, part of Bio-Techne
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NB110-93362
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse, Rat, Sheep

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all CNPase Antibodies »

Product Specifications

Immunogen

Endogenous rabbit 2,3 cyclic nucleotide-3-phospho-diesterase. Accession # P13233

Specificity

Specific for endogenous levels of the ~46 kDa CNPase protein.

Marker

Oligodendrocyte Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage).

Scientific Data Images for CNPase Antibody - Azide and BSA Free

Western Blot: CNPase AntibodyAzide and BSA Free [NB110-93362]

Western Blot: CNPase AntibodyAzide and BSA Free [NB110-93362]

Western Blot: CNPase Antibody [NB110-93362] - Rat brain lysate showing the specific immunolabeling of the ~ 46k CNP protein.
Immunohistochemistry-Frozen: CNPase Antibody - Azide and BSA Free [NB110-93362]

Immunohistochemistry-Frozen: CNPase Antibody - Azide and BSA Free [NB110-93362]

Immunohistochemistry-Frozen: CNPase Antibody [NB110-93362] - Staining of saline treated mouse cortex cryosections with CNPase antibody (green). Cell nuclei are visualized with DAPI DNA stain (blue).

Applications for CNPase Antibody - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:1000

Immunohistochemistry-Frozen

1:500-1:1000

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Neat whole antisera

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CNPase

2,3-cyclic nucleotide-3-phosphodiesterase (CNP) is a membrane bound, microtubule associated protein that is among the most abundant myelin proteins of the CNS. It is thought that CNP may serve as a regulator of tubulin polymerization and of microtubule distribution (Bifulco et al., 2002). It was recently found that CNP may also function as a possible linker protein anchoring microtubules to the plasma membrane via a 13 residue C-terminal CNP fragment (Bifulco et al., 2002, Esposito et al., 2008).

Alternate Names

2', 3' cyclic nucleotide 3' phosphohydrolase, 2'-3'-cyclic nucleotide 3' phosphodiesterase, 2'-3'-cyclic-nucleotide 3'-phosphodiesterase, CNP1, CNPase, EC 3.1.4.37

Entrez Gene IDs

1267 (Human); 12799 (Mouse); 25275 (Rat)

Gene Symbol

CNP

UniProt

P13233 (Rat)

Additional CNPase Products

Product Documents for CNPase Antibody - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CNPase Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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