Coagulation Factor II/Thrombin Antibody (GMA-020)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-29813

Novus Biologicals, part of Bio-Techne
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NBP2-29813
NBP2-29813-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # GMA-020

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Coagulation Factor II/Thrombin Antibodies »

Product Summary for Coagulation Factor II/Thrombin Antibody (GMA-020)

Immunogen

purified human thrombin.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Relevant Entrez Gene Numbers: NM_000506

Scientific Data Images for Coagulation Factor II/Thrombin Antibody (GMA-020)

Western Blot: Coagulation Factor II/Thrombin Antibody (GMA-020) [NBP2-29813]

Western Blot: Coagulation Factor II/Thrombin Antibody (GMA-020) [NBP2-29813]

Western Blot: Coagulation Factor II/Thrombin Antibody (GMA-020) [NBP2-29813] - 2ug of human thrombin was probed with anti-Thrombin, clone GMA-020 (1ug/ml). Arrow indicates thrombin (non reduced) (~31kDa).

Applications for Coagulation Factor II/Thrombin Antibody (GMA-020)

Application
Recommended Usage

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS with 1.0% mannitol, pH 7.4

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Coagulation Factor II/Thrombin

Proteinase-activated receptor 3 (PAR3) is a member of the Proteinase-Activated Receptor subfamily. The enzyme thrombin is involved in the activation of platelets, leukocytes, endothelial cells, and mesenchymal cells at sites of vascular injury. These cellular responses are triggered through proteolytic activation of PAR3 and other receptors by thrombin. It is believed that PAR3 functions as a cofactor for the cleavage and activation of PAR4. PAR3 expression has been documented in blood, bone marrow, lung, spleen, and vessel. ESTs have been isolated from head/neck, skeletal muscle, and skin libraries.

Alternate Names

F2, Thrombin

Gene Symbol

F2

UniProt

P00734

Additional Coagulation Factor II/Thrombin Products

Product Documents for Coagulation Factor II/Thrombin Antibody (GMA-020)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Coagulation Factor II/Thrombin Antibody (GMA-020)

Relevant Entrez Gene Numbers: NM_000506

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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