Coagulation Factor XI Antibody (MM0193-7C38) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12199JF646

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Block/Neutralize, Western Blot

Label

Janelia Fluor 646

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0193-7C38

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Coagulation Factor XI Antibodies »

Product Specifications

Immunogen

Human recombinant Coagulation Factor XI

Reactivity Notes

0

Specificity

Detects human Coagulation factor XI (Light Chain)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Applications for Coagulation Factor XI Antibody (MM0193-7C38) [Janelia Fluor® 646]

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Coagulation Factor XI

Factor XI encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq]

Alternate Names

coagulation factor XI, EC 3.4.21, EC 3.4.21.27, FXIPlasma thromboplastin antecedent, MGC141891, PTA

Gene Symbol

F11

Additional Coagulation Factor XI Products

Product Documents for Coagulation Factor XI Antibody (MM0193-7C38) [Janelia Fluor® 646]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Coagulation Factor XI Antibody (MM0193-7C38) [Janelia Fluor® 646]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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