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Complement Component C1s Antibody (sutimlimab) - Humanized, IgG4SP

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28049

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-28049-100ug
NBP3-28049-50ug

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG4 Clone # sutimlimab

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

C1s

Clonality

Monoclonal

Host

Human

Isotype

IgG4

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Description

Expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'sutimlimab'.

IgG4SP is human IgG4 with S228P mutation.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Complement Component C1s Antibody (sutimlimab) - Humanized, IgG4SP

Complement Component C1s Antibody (sutimlimab) - Humanized, IgG4SP

ELISA: Complement Component C1s Antibody (sutimlimab) - Humanized, IgG4SP[NBP3-28049] -

Immobilized human C1S His at 2 ug/mL can bind Complement Component C1s Antibody (sutimlimab) - Humanized, IgG4SP, EC50=0.006163 ug/mL.

Applications for Complement Component C1s Antibody (sutimlimab) - Humanized, IgG4SP

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Complement Component C1s

C1s encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq]

Alternate Names

C1S

Gene Symbol

C1S

UniProt

Additional Complement Component C1s Products

Product Documents for Complement Component C1s Antibody (sutimlimab) - Humanized, IgG4SP

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Complement Component C1s Antibody (sutimlimab) - Humanized, IgG4SP

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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