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Complement Factor H-related 5/CFHR5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14912

Novus Biologicals, part of Bio-Techne
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NBP2-14912

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Complement Factor H-related 5/CFHR5. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Complement Factor H-related 5/CFHR5 Antibody

Western Blot: Complement Factor H-related 5/CFHR5 Antibody [NBP2-14912]

Western Blot: Complement Factor H-related 5/CFHR5 Antibody [NBP2-14912]

Western Blot: CFHR5 Antibody [NBP2-14912] - Sample (30 ug of whole cell lysate) A: HepG2 7. 5% SDS PAGE, antibody diluted at 1:3000.
Immunohistochemistry-Paraffin: Complement Factor H-related 5/CFHR5 Antibody [NBP2-14912]

Immunohistochemistry-Paraffin: Complement Factor H-related 5/CFHR5 Antibody [NBP2-14912]

Immunohistochemistry-Paraffin: CFHR5 Antibody [NBP2-14912] - Paraffin-embedded Hepatoma, using antibody at 1:500 dilution.

Applications for Complement Factor H-related 5/CFHR5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Complement Factor H-related 5/CFHR5

This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq]

Alternate Names

CFHL5, CFHR5, Complement Factor Hrelated 5, FHR5

Gene Symbol

CFHR5

UniProt

Additional Complement Factor H-related 5/CFHR5 Products

Product Documents for Complement Factor H-related 5/CFHR5 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Complement Factor H-related 5/CFHR5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.