Connexin 26/GJB2 Antibody [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41304CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP2-41304AF350

Alexa Fluor 405

NBP2-41304AF405

Alexa Fluor 488

NBP2-41304AF488

Alexa Fluor 532

NBP2-41304AF532

Alexa Fluor 594

NBP2-41304AF594

Alexa Fluor 647

NBP2-41304AF647

Alexa Fluor 700

NBP2-41304AF700

Alexa Fluor 750

NBP2-41304AF750

Biotin

NBP2-41304B

DyLight 350

NBP2-41304UV

DyLight 405

NBP2-41304V

DyLight 488

NBP2-41304G

DyLight 550

NBP2-41304R

DyLight 594

NBP2-41304DL594

DyLight 650

NBP2-41304C

DyLight 680

NBP2-41304FR

DyLight 755

NBP2-41304IR

FITC

NBP2-41304F

HRP

NBP2-41304H

Janelia Fluor 525

NBP2-41304JF525

Janelia Fluor 549

NBP2-41304JF549

Janelia Fluor 585

NBP2-41304JF585

Janelia Fluor 635

NBP2-41304JF635

Janelia Fluor 646

NBP2-41304JF646

Janelia Fluor 669

NBP2-41304JF669

mFluor Violet 450 SE

NBP2-41304MFV450

mFluor Violet 500 SE

NBP2-41304MFV500

mFluor Violet 610 SE

NBP2-41304MFV610

PerCP

NBP2-41304PCP

Forumulation

Catalog #

BSA Free

NBP2-41304

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Rat, Porcine

Predicted:

Mouse (94%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

CoraFluor 1

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Connexin 26/GJB2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid peptide near the center of human GJB2. The immunogen is located within amino acids 80 - 130 of GJB2. Amino Acid Squence: HVAYRRHEKKRKFIKGE

Reactivity Notes

Predicted species reactivity based on immunogen sequence: Sheep: (88%), Bovine: (88%), Chicken: (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for Connexin 26/GJB2 Antibody [CoraFluor™ 1]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Connexin 26/GJB2

Connexin-26 / GJB2 is a gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-26 belongs to the class 1 (beta) group of connexins. Mutations in Connexin-26 are associated with genetically derived hearing impairments, including autosomal recessive non syndromic deafness.

Alternate Names

CX26, DFNA3, DFNB1, GJB2, HID, KID, NSRD1, PPK

Gene Symbol

GJB2

Additional Connexin 26/GJB2 Products

Product Documents for Connexin 26/GJB2 Antibody [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Connexin 26/GJB2 Antibody [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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