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Connexin 30/GJB6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-45247

Novus Biologicals, part of Bio-Techne
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NBP1-45247

Key Product Details

Species Reactivity

Human, Mouse, Rat, Bovine

Applications

Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-RSKRAQTQKNHPNH corresponding to internal region according to NP_006774.2.

Epitope

internal region

Specificity

Reported variants represent identical protein: NP_006774.2, NP_001103691.1, NP_001103689.1, NP_001103690.1

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Applications for Connexin 30/GJB6 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000
Application Notes
WB: Preliminary experiments gave an approx. 14 kDa band in human brain (cerebellum) and rat brain lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 30.4 kDa band according to NP_006774.2. The 14 kDa band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Connexin 30/GJB6

The connexin gene family codes for the protein subunits of gap junction channels that mediate direct diffusion of ions and metabolites between the cytoplasm of adjacent cells. Connexins span the plasma membrane 4 times, with amino- and carboxy-terminal regions facing the cytoplasm. Connexin genes are expressed in a cell type-specific manner with overlapping specificity. The gap junction channels have unique properties depending on the type of connexins constituting the channel.[supplied by OMIM]

Alternate Names

CX30, DFNA3B, DFNB1B, ED2, EDH, GJB6

Entrez Gene IDs

10804 (Human); 14623 (Mouse); 84403 (Rat)

Gene Symbol

GJB6

Additional Connexin 30/GJB6 Products

Product Documents for Connexin 30/GJB6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Connexin 30/GJB6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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