Connexin 43/GJA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB110-55546

Novus Biologicals, part of Bio-Techne
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NB110-55546
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Hamster, Monkey, Primate, Rabbit

Predicted:

Bat (94%), Chicken (94%), Equine (94%), Opossum (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all Connexin 43/GJA1 Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from C-terminus of human Connexin 43/GJA1.

Epitope

C-terminal domain of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Zebrafish (81%).

Specificity

Human Connexin 43/GJA1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Marker

Gap Junctions Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Connexin 43/GJA1 Antibody

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NB110-55546]

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NB110-55546]

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NB110-55546] - Analysis of anti-GJA1 / Connexin 43 antibody with human testis, seminiferous tubules and Leydig cells at concentration 20 ug/ml.

Applications for Connexin 43/GJA1 Antibody

Application
Recommended Usage

Immunohistochemistry

10-20 ug/ml

Immunohistochemistry-Paraffin

10-20 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Connexin 43/GJA1

GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5.

Alternate Names

CX43, GJA1, GJAL, ODDD, ODOD, SDTY3

Entrez Gene IDs

2697 (Human)

Gene Symbol

GJA1

Additional Connexin 43/GJA1 Products

Product Documents for Connexin 43/GJA1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Connexin 43/GJA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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