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Copeptin Antibody (C1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41506

Novus Biologicals, part of Bio-Techne
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NBP3-41506

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # C1

Concentration

1 mg/ml

Product Specifications

Immunogen

Immunized with Human Copeptin (Uniprot#: P01185; Immunogen sequence: Asp128-Leu144 (Uniprot#: P01185)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for Copeptin Antibody (C1)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS, pH7.4, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Copeptin

Copeptin is a 39 amino acid glycosylated peptide that is a proteolytic product derived from a precursor which also contains Vasopressin and Neurophysin 2 peptides. The precursor protein is synthesized and cleaved in the hypothalamus before transport to the pituitary for storage and release. Copeptin is more stable than Vasopressin and serves as a surrogate indicator of Vasopressin release. Vasopressin plays a major role in blood pressure regulation through control of water retention in the kidney and vascular tone. Serum levels of Copeptin are associated with metabolic syndrome, insulin resistance, sepsis, and heart dysfunction following myocardial infarction.

Alternate Names

ADH;ARVP;AVP;AVP-NPII;AVRP;Vasopressin-neurophysin 2-copeptin;VP

Gene Symbol

AVP

Additional Copeptin Products

Product Documents for Copeptin Antibody (C1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Copeptin Antibody (C1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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