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COPS8 Antibody (SR1315)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22549

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-22549-100ul
NBP3-22549-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1315

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for COPS8 Antibody (SR1315)

Immunogen

A synthesized peptide derived from human COPS8 (Uniprot #: Q99627)

Specificity

Detects endogenous levels of total COPS8

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for COPS8 Antibody (SR1315)

Western Blot: COPS8 Antibody (SR1315) [NBP3-22549] -

Western Blot: COPS8 Antibody (SR1315) [NBP3-22549] - Western blot analysis using NBP3-22549 in HepG2 cell lysate.

Applications for COPS8 Antibody (SR1315)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: COPS8

COPS8 is encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternate Names

COP9, COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis), COP9 homolog, COP9 signalosome complex subunit 8, CSN8JAB1-containing signalosome subunit 8, hCOP9, MGC1297, MMMEP, SGN8MGC43256, Signalosome subunit 8

Gene Symbol

COPS8

Additional COPS8 Products

Product Documents for COPS8 Antibody (SR1315)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for COPS8 Antibody (SR1315)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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