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Coronin-2B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85567

Novus Biologicals, part of Bio-Techne
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NBP1-85567
NBP1-85567-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Mouse

Predicted:

Mouse (97%), Rat (96%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFKAPIKEKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Coronin-2B Antibody

Immunocytochemistry/ Immunofluorescence: Coronin-2B Antibody [NBP1-85567]

Immunocytochemistry/ Immunofluorescence: Coronin-2B Antibody [NBP1-85567]

Immunocytochemistry/Immunofluorescence: Coronin-2B Antibody [NBP1-85567] - Staining of human cell line U-251 MG shows localization to plasma membrane & focal adhesion sites. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Coronin-2B Antibody [NBP1-85567]

Immunohistochemistry-Paraffin: Coronin-2B Antibody [NBP1-85567]

Immunohistochemistry-Paraffin: Coronin-2B Antibody [NBP1-85567] - Staining of human fallopian tube shows weak membranous/cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Coronin-2B Antibody [NBP1-85567]

Immunohistochemistry-Paraffin: Coronin-2B Antibody [NBP1-85567]

Immunohistochemistry-Paraffin: Coronin-2B Antibody [NBP1-85567] - Analysis in human cerebral cortex and liver tissues. Corresponding CORO2B RNA-seq data are presented for the same tissues.

Applications for Coronin-2B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Coronin-2B

Research results indicate that ClipinC is a component part of the cross bridge between the actin cytoskeleton and the plasma membrane. These findings and the previously reported function of coronin suggest that ClipinC may play specific roles in the reorganization of neuronal actin structure, a change that has been implicated in both cell motility and growth cone advance.

Alternate Names

clipin C, CLIPINC, Clipin-C, coronin, actin binding protein, 2B, coronin, actin-binding protein, 2B, coronin, actin-binding, 2B, coronin-2B, Coronin-like protein C, KIAA0925clipin-C, Protein FC96

Gene Symbol

CORO2B

Additional Coronin-2B Products

Product Documents for Coronin-2B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Coronin-2B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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