Cortistatin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-69148

Novus Biologicals, part of Bio-Techne
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NBP1-69148
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Applications

Validated:

ELISA, Western Blot

Cited:

ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Cortistatin Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to CORT (cortistatin) The peptide sequence was selected from the N terminal of CORT. Peptide sequence MPLSPGLLLLLLSGATATAALPLEGGPTGRDSEHMQEAAGIRKSSLLTFL. The peptide sequence for this immunogen was taken from within the described region.

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 30181699).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Cortistatin Antibody

Western Blot: Cortistatin Antibody [NBP1-69148]

Western Blot: Cortistatin Antibody [NBP1-69148]

Western Blot: Cortistatin Antibody [NBP1-69148] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

Applications for Cortistatin Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Application Notes
Use in ELISA reported in scientific literature (PMID: 30181699).

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cortistatin

This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.

Alternate Names

cortistatin, cortistatin-14, cortistatin-17, cortistatin-29, CST-14, CST-17, CST-29, MGC32686, preprocortistatin

Gene Symbol

CORT

Additional Cortistatin Products

Product Documents for Cortistatin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Cortistatin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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