COX-1 Antibody (S02-6G4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19609

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19609-100ul
NBP3-19609-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S02-6G4

Concentration

0.3 mg/ml

View all COX-1 Antibodies »

Product Summary for COX-1 Antibody (S02-6G4)

Immunogen

A synthetic peptide of human COX-1 (Uniprot # P23219)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

69 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for COX-1 Antibody (S02-6G4)

Western Blot: COX-1 Antibody (S02-6G4) [NBP3-19609]

Western Blot: COX-1 Antibody (S02-6G4) [NBP3-19609]

Western Blot: COX-1 Antibody (S02-6G4) [NBP3-19609] - Western blot detection of COX-1 in C6, 3T3 cell lysates using NBP3-19609 (1:1000 diluted). Predicted band size: 69kDa. Observed band size: 69kDa.
Immunocytochemistry/ Immunofluorescence: COX-1 Antibody (S02-6G4) [NBP3-19609]

Immunocytochemistry/ Immunofluorescence: COX-1 Antibody (S02-6G4) [NBP3-19609]

Immunocytochemistry/Immunofluorescence: COX-1 Antibody (S02-6G4) [NBP3-19609] - Immunofluorescence of COX-1 (green) in Hela cells using NBP3-19609 at dilution 1/200, and DAPI (blue)
Immunohistochemistry-Paraffin: COX-1 Antibody (S02-6G4) [NBP3-19609]

Immunohistochemistry-Paraffin: COX-1 Antibody (S02-6G4) [NBP3-19609]

Immunohistochemistry-Paraffin: COX-1 Antibody (S02-6G4) [NBP3-19609] - Immunohistochemistry of COX-1 in paraffin-embedded Human colon cancer tissue using NBP3-19609 at dilution 1/5

Applications for COX-1 Antibody (S02-6G4)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/20-1/100

Immunohistochemistry

1/50-1/200

Western Blot

1/1000-1/2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: COX-1

Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.

Long Name

Cyclooxygenase 1

Alternate Names

COX1, PTGS1

Gene Symbol

PTGS1

Additional COX-1 Products

Product Documents for COX-1 Antibody (S02-6G4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for COX-1 Antibody (S02-6G4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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