COX-2 Antibody (RM348)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-77419

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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NBP2-77419
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM348

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all COX-2 Antibodies »

Product Summary for COX-2 Antibody (RM348)

Immunogen

A peptide corresponding to the C-terminus of human COX-2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for COX-2 Antibody (RM348)

Western Blot: COX-2 Antibody (RM348) [NBP2-77419]

Western Blot: COX-2 Antibody (RM348) [NBP2-77419]

Western Blot: COX-2 Antibody (RM348) [NBP2-77419] - HeLa cell lysate using anti-COX-2 rabbit monoclonal antibody (Clone RM348) at a 1:20000 dilution.
Immunohistochemistry-Paraffin: COX-2 Antibody (RM348) [NBP2-77419]

Immunohistochemistry-Paraffin: COX-2 Antibody (RM348) [NBP2-77419]

Immunohistochemistry-Paraffin: COX-2 Antibody (RM348) [NBP2-77419] - Human lung cancer tissue section using anti-COX-2 rabbit monoclonal antibody (Clone RM348) at a 1:1000 dilution.

Applications for COX-2 Antibody (RM348)

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Western Blot

1:1000 - 1:20000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: COX-2

COX2 (Cyclooxygenase 2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.

Long Name

Cyclooxygenase 2

Alternate Names

COX2, PGHS-2, PHS-II, PTGS2

Gene Symbol

PTGS2

Additional COX-2 Products

Product Documents for COX-2 Antibody (RM348)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for COX-2 Antibody (RM348)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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