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CPOX Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33665

Novus Biologicals, part of Bio-Techne
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NBP1-33665

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (94%), Porcine (94%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for CPOX Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human CPOX. The exact sequence is proprietary.

Reactivity Notes

Mouse (89%), Rat (88%).

Localization

Mitochondrion intermembrane space

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CPOX Antibody

Western Blot: CPOX Antibody [NBP1-33665]

Western Blot: CPOX Antibody [NBP1-33665]

Western Blot: CPOX Antibody [NBP1-33665] - Sample (30 ug of whole cell lysate) A: HCT116 10% SDS PAGE; antibody diluted at 1:1000.

Applications for CPOX Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CPOX

The protein encoded by the CPOX gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is solubleand found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation ofcoproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditarycoproporphyria (HCP).

Alternate Names

Coprogen oxidase, coproporphyrinogen oxidase, Coproporphyrinogenase, coproporphyrinogen-III oxidase, mitochondrial, COX, CPO, CPXcoproporphyrinogen oxidase (coproporphyria, harderoporphyria), EC 1.3.3.3, HCP

Gene Symbol

CPOX

Additional CPOX Products

Product Documents for CPOX Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CPOX Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.