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CRMP5 Antibody (5L4S8)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16204

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16204-100ul
NBP3-16204-20ul

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 5L4S8

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 465-564 of human CRMP5 (Q9BPU6). RSFPDTVYKKLVQREKTLKVRGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CRMP5 Antibody (5L4S8)

Western Blot: CRMP5 Antibody (5L4S8) [NBP3-16204]

Western Blot: CRMP5 Antibody (5L4S8) [NBP3-16204]

Western Blot: CRMP5 Antibody (5L4S8) [NBP3-16204] - Western blot analysis of extracts of various cell lines, using CRMP5 Rabbit mAb (NBP3-16204) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Immunohistochemistry-Paraffin: CRMP5 Antibody (5L4S8) [NBP3-16204]

Immunohistochemistry-Paraffin: CRMP5 Antibody (5L4S8) [NBP3-16204]

Immunohistochemistry-Paraffin: CRMP5 Antibody (5L4S8) [NBP3-16204] - Immunohistochemistry of paraffin-embedded human appendix using CRMP5 Rabbit mAb (NBP3-16204) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry-Paraffin: CRMP5 Antibody (5L4S8) [NBP3-16204]

Immunohistochemistry-Paraffin: CRMP5 Antibody (5L4S8) [NBP3-16204]

Immunohistochemistry-Paraffin: CRMP5 Antibody (5L4S8) [NBP3-16204] - Immunohistochemistry of paraffin-embedded rat spleen using CRMP5 Rabbit mAb (NBP3-16204) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Applications for CRMP5 Antibody (5L4S8)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CRMP5

The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.

Alternate Names

Collapsin response mediator protein 5, collapsin response mediator protein-5, CRAMCRMP3-associated molecule, CRMP-5FLJ45383, CRMP5UNC33-like phosphoprotein 6, dihydropyrimidinase-like 5, dihydropyrimidinase-related protein 5, DRP-5, Ulip6, ULIP-6

Gene Symbol

DPYSL5

Additional CRMP5 Products

Product Documents for CRMP5 Antibody (5L4S8)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CRMP5 Antibody (5L4S8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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