CRMP5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33419

Novus Biologicals, part of Bio-Techne
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NBP1-33419
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (99%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CRMP5 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human CRMP5. The exact sequence is proprietary.

Localization

Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CRMP5 Antibody

Western Blot: CRMP5 Antibody [NBP1-33419]

Western Blot: CRMP5 Antibody [NBP1-33419]

Western Blot: CRMP5 Antibody [NBP1-33419] - Mouse tissue extract (5 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with CRMP5 antibody [N1C1] diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: CRMP5 Antibody [NBP1-33419]

Immunocytochemistry/ Immunofluorescence: CRMP5 Antibody [NBP1-33419]

Immunocytochemistry/Immunofluorescence: CRMP5 Antibody [NBP1-33419] - DIV10 rat E18 primary cortical neurons were fixed in 4% paraformaldehyde at RT for 15 min.Green: CRMP5 protein stained by CRMP5 antibody [N1C1] diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody [1338] diluted at 1:500. Blue: Fluoroshield with DAPI.
Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-33419]

Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-33419]

Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-33419] - Paraffin-embedded mouse lung. CRMP5 antibody [N1C1] diluted at 1:500.
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Applications for CRMP5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:20000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CRMP5

The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.

Alternate Names

Collapsin response mediator protein 5, collapsin response mediator protein-5, CRAMCRMP3-associated molecule, CRMP-5FLJ45383, CRMP5UNC33-like phosphoprotein 6, dihydropyrimidinase-like 5, dihydropyrimidinase-related protein 5, DRP-5, Ulip6, ULIP-6

Gene Symbol

DPYSL5

Additional CRMP5 Products

Product Documents for CRMP5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CRMP5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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