CRMP5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85461

Novus Biologicals, part of Bio-Techne
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NBP1-85461
NBP1-85461-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CRMP5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRGVDRTPYL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CRMP5 Antibody

Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-85461]

Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-85461]

Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-85461] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-85461]

Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-85461]

Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-85461] - Staining of human lateral ventricle shows moderate cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-85461]

Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-85461]

Immunohistochemistry-Paraffin: CRMP5 Antibody [NBP1-85461] - Staining of human cerebral cortex shows high expression.
View 1 more images

Applications for CRMP5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRMP5

The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.

Alternate Names

Collapsin response mediator protein 5, collapsin response mediator protein-5, CRAMCRMP3-associated molecule, CRMP-5FLJ45383, CRMP5UNC33-like phosphoprotein 6, dihydropyrimidinase-like 5, dihydropyrimidinase-related protein 5, DRP-5, Ulip6, ULIP-6

Gene Symbol

DPYSL5

Additional CRMP5 Products

Product Documents for CRMP5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CRMP5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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