CRTAC1 (cartilage acidic protein 1; also CEP-68) is a 95-105 kDa member of a novel family of EGF domain-containing proteins. It is secreted by articular chondrocytes and may play a role in either cartilage matrix organization, or cell-matrix adhesion. Mature human CRTAC1 is 634 amino acids (aa) in length. It contains four FG-GAP (PheGly-GlyAlaPro) domains (aa 46-437) and one EGF-like motif (aa 559-605). Multiple splice forms exist. There are two alternate start sites at Met9 and Met211 that may be accompanied by a 39 aa substitution for the C-terminal 55 aa, or an 84 aa substitution for aa 545-661. Over aa 28-661, human CRTAC1 shares 91% aa identity with mouse CRTAC1. This form in mouse, however, is more equivalent to the human isoform that shows a C-terminal 39 aa substitution. In this case, there is 95% aa identity between mouse and human.

Long Name

Cartilage Acidic Protein 1

Alternate Names

ASPIC1, CEP68

Gene Symbol

CRTAC1

Additional CRTAC1 Products

Product Documents for CRTAC1 Antibody [DyLight 405]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for CRTAC1 Antibody [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

CRTAC1 Antibody [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98935V

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all CRTAC1 Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Applications for CRTAC1 Antibody [DyLight 405]

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: CRTAC1